# Endoscopic versus laparoscopic resection of gastrointestinal stromal tumors at the esophagogastric junction using propensity score matching analysis

Researcher: Ge Zhang
Chinese name: 张格
ORCID identity anchor: https://orcid.org/0000-0002-3116-3246
Canonical researcher: https://drgezhang.com/#person

Journal: Scientific Reports
Year: 2025
Type: Article
DOI: 10.1038/s41598-025-98859-3
Canonical page: https://drgezhang.com/papers/doi-10-1038-s41598-025-98859-3.html
Markdown record: https://drgezhang.com/papers/doi-10-1038-s41598-025-98859-3.md

## Full Authors

1. Shanshan Zhu
2. Zhen Liu
3. Jingwen Zhang
4. Nan Dai
5. Saif Ullah
6. Ge Zhang
7. Shengang Zhang
8. Ping Liu
9. Yang Fu
10. Shimeng Zheng
11. Zhaokai Zhou
12. Yudi Xu
13. Le Chang
14. Changqing Guo
15. Xinguang Cao

## About this record

This is an author-controlled publication record in the Ge Zhang Academic Hub. It identifies this work as part of Ge Zhang’s publication record via ORCID; the publisher version remains the version of record.

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## Research context and source limits

Limited evidence note. Only the source material identified below has been reviewed; this is not a complete Paper GEO V2 assessment.

Study design and unresolved matching integrity; treatment comparisons are not verified.

### Research question and design

This single-centre retrospective study compared endoscopic and laparoscopic resection for pathologically confirmed gastrointestinal stromal tumours at the esophagogastric junction. The stated study window was December 2013 to November 2023, and eligibility focused on tumours measuring 2–5 cm. This is an observational treatment comparison, not a randomized trial.

Source: [Methods: Study design and patients; Figure 1](https://www.nature.com/articles/s41598-025-98859-3)

### How treatment groups were compared

The authors describe nearest-neighbour propensity matching at a 1:1 ratio, using age, sex, tumour size, mitotic count and risk classification. This establishes the reported analytical approach; it does not verify that matching achieved balance or removed unmeasured confounding. No comparative safety, recovery or oncological benefit is endorsed here.

Source: [Methods: Statistical analysis; Tables 1–3](https://www.nature.com/articles/s41598-025-98859-3)

### Unresolved source conflict

The abstract reverses the unmatched ER/LR allocation relative to the Results and Table 1. More substantially, the matched laparoscopic group is labelled n=20 but lists 10 males and 20 females. The formal PDF confirms the table inconsistency, so matched-group balance remains unverified.

Source: [Abstract versus Results: Baseline clinicopathologic characteristics; Table 1 after PSM, LR Gender; publisher PDF p. 5](https://www.nature.com/articles/s41598-025-98859-3)

### Evidence limits

- Reported methods are summarized without adopting disputed participant allocations.
- A corrected allocation and matching table are required before a complete V2 comparison.

### Provenance

- [Article source](https://www.nature.com/articles/s41598-025-98859-3) — Official publisher or PMC full text reviewed locally. Methods: Study design and patients; Figure 1

Source review: 2026-10-27.

## Cite this paper

Shanshan Zhu, Zhen Liu, Jingwen Zhang, Nan Dai, Saif Ullah, Ge Zhang, Shengang Zhang, Ping Liu, Yang Fu, Shimeng Zheng, Zhaokai Zhou, Yudi Xu, Le Chang, Changqing Guo, Xinguang Cao. Endoscopic versus laparoscopic resection of gastrointestinal stromal tumors at the esophagogastric junction using propensity score matching analysis. Scientific Reports. 2025. https://doi.org/10.1038/s41598-025-98859-3

- [BibTeX](https://drgezhang.com/citations/doi-10-1038-s41598-025-98859-3.bib)
- [RIS / EndNote](https://drgezhang.com/citations/doi-10-1038-s41598-025-98859-3.ris)
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## Links

- DOI: https://doi.org/10.1038/s41598-025-98859-3
- HTML page: https://drgezhang.com/papers/doi-10-1038-s41598-025-98859-3.html
- Google Scholar query: https://scholar.google.com/scholar?q=%22Endoscopic%20versus%20laparoscopic%20resection%20of%20gastrointestinal%20stromal%20tumors%20at%20the%20esophagogastric%20junction%20using%20propensity%20score%20matching%20analysis%22
- ORCID: https://orcid.org/0000-0002-3116-3246