Article · 2023 Deep GEO

Idebenone attenuates ferroptosis by inhibiting excessive autophagy via the ROS-AMPK-mTOR pathway to preserve cardiac function after myocardial infarction

European Journal of Pharmacology

Why this study matters

A mechanistic study linking idebenone-mediated cardioprotection after myocardial infarction to ROS, autophagy, ferroptosis and AMPK–mTOR signaling.

idebenoneferroptosisautophagyROSAMPKmTORmyocardial infarction

Questions this paper can answer

  1. Does idebenone suppress ferroptosis after myocardial infarction?
  2. How are ROS, autophagy and AMPK–mTOR linked in post-MI injury?
  3. What mechanisms underlie idebenone cardioprotection?
Author-controlled academic record for Ge Zhang. This page identifies the work as part of Ge Zhang’s publication record via ORCID 0000-0002-3116-3246. It does not replace the publisher version or assert a complete author list.